Endometriosis Research Today is a free monthly online journal that collates and summarizes the latest research about Endometriosis, including details on causes, treatment, symptoms, infertility.

A pilot study on the off-label use of valproic acid to treat adenomyosis.

Liu X, Guo SW

Department of Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China. lxsdoc@hotmail.com

Following on the heels of the discovery that endometriosis is an epigenetic disease, we conducted a pilot study on the off-label use of valproic acid to treat adenomyosis. We found that by the end of the 3-month treatment, all three recruited patients reported complete disappearance of dysmenorrhea, with an average of one-third reduction in uterus size.

Published 14 January 2008 in Fertil Steril, 89(1): 246-50.
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