Endometriosis Research - Causes, Treatment, Symptoms, Infertility

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Clinical pitfalls of pain recurrence in endometriosis arising in the posterior vaginal fornix.

Tachibana M, Murakami T, Utsunomiya H, Terada Y, Yaegashi N, Okamura K

Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan. masahito@mail.tains.tohoku.ac.jp

Endometriotic nodules in the lower genital tract often cause dysmenorrhea and dyspareunia. We report here a case of posterior vaginal fornix endometriosis that was overlooked for several years. We performed a trans-vaginal resection after the associated pain was not relieved by repetitive gonadotropin-releasing hormone agonist (GnRHa) therapy or abdominal surgery. After the resection, the patient's symptoms disappeared. The patient subsequently conceived and proceeded to a full-term delivery. The pathological diagnosis was 'endometriosis of the vagina.' Immunohistochemical staining revealed that the progesterone receptor-positive cells outnumbered the estrogen receptor-positive cells. We emphasize that the existence of vaginal lesions should be considered in cases in which pain has not improved despite long-term GnRHa administration, or in cases involving dyspareunia. To provide appropriate treatment, attentive evaluation and careful examination of the disease are necessary for a patient with prolonged unsatisfactory progress.

Published 19 April 2007 in J Obstet Gynaecol Res, 33(2): 207-10.
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Endometriosis Research Today Archive:

Volume 1 (2004)
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