Endometriosis Research Today is a free monthly online journal that collates and summarizes the latest research about Endometriosis, including details on causes, treatment, symptoms, infertility.

Effect of the immunomodulator leflunomide on the induction of endometriosis in an experimental rat model.

Aytan H, Caglar P, Uygur D, Zergeroglu S, Batioglu S

The effect of immunomodulator leflunomide on the development of an experimental endometriosis model was assessed by surgically transplanting autologous fragments of endometrial tissue onto the inner surface of the abdominal wall and arterial cascades of the small intestines. Leflunomide was found to affect the development of endometriosis negatively and seemed to interfere with the growth and maintenance of the uterine explant in this experimental rat model.

Published 16 March 2007 in Fertil Steril, 87(3): 698-701.
Full-text of this article is available online (may require subscription).

© 2004-2008 Endometriosis Research Today. All Rights Reserved.